首页> 外国专利> METHOD FOR OBTAINING PLATELET-DERIVED MITOCHONDRIA AND USE THEREOF

METHOD FOR OBTAINING PLATELET-DERIVED MITOCHONDRIA AND USE THEREOF

机译:获得血小板衍生的线粒体的方法及其用途

摘要

The present invention relates to a method for obtaining active mitochondria by freezing platelets and the use of isolated mitochondria, and more particularly, to a method for obtaining mitochondria by freezing and thawing platelets and effectively using the mitochondria obtained by the method It relates to a pharmaceutical composition comprising as an ingredient. The present invention provides a method for obtaining mitochondria by thawing platelets frozen in a preservative solution, so that not only mitochondria with stable activity can be easily obtained, but also commercial value for donor platelets that are discarded after refrigeration for a short period of time can also be provided. In addition, the pharmaceutical composition comprising the platelet-derived mitochondria obtained by the above method can be usefully used to treat various diseases caused by mitochondrial dysfunction.
机译:本发明涉及通过冷冻血小板和分离的线粒体的使用,更具体地,通过冷冻和解冻血小板来获得线粒体的方法和使用通过通过其涉及药物的方法获得的线粒体获得线粒体获得线粒体的方法组合物包含成分。本发明提供了通过在防腐溶液中冷冻的血小板来获得线粒体的方法,因此不仅可以容易地获得具有稳定活性的线粒体,而且还可以容易地获得稳定的活性,而且在制冷后丢弃的供体血小板的商业价值可以很短的时间丢弃也提供。此外,包含通过上述方法获得的血小板衍生的线粒体的药物组合物可以用来用来治疗由线粒体功能障碍引起的各种疾病。

著录项

  • 公开/公告号KR102273163B1

    专利类型

  • 公开/公告日2021-07-05

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020200116297

  • 发明设计人 강영철;한규범;하종천;

    申请日2020-09-10

  • 分类号C12N5/078;A01N1/02;A61K35/19;A61P29;A61P9/10;

  • 国家 KR

  • 入库时间 2024-06-14 21:49:43

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