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Microbead And Nanofiber Based Controlled Drug Release System

机译:微珠和基于纳米纤维的受控药物释放系统

摘要

Various examples are provided for controlled drug release over an extended period of time. In one example, a controlled release system includes a multilayer membrane including a first biocompatible nanofiber layer; a microbead layer disposed on the first biocompatible nanofiber layer, the microbeads comprising a releasable agent; and a second biocompatible nanofiber layer disposed over the microbead layer. The first and second biocompatible nanofiber layers support the microbead layer and provide a diffusion barrier that can control a release profile of the releasable agent.
机译:提供各种实例以在延长的时间内提供受控药物释放。在一个实例中,受控释放系统包括包括第一生物相容性纳米纤维层的多层膜;设置在第一生物相容性纳米纤维层上的微珠层,微珠包含可释放剂;和设置在微珠层上的第二生物相容性纳米纤维层。第一和第二生物相容性纳米纤维层支撑微珠层并提供可以控制可释放剂的释放曲线的扩散屏障。

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