首页> 外国专利> NATURAL NANOPARTICLE-MEDICINE COMPOSITION FOR TREATING ALZHEIMER'S DISEASE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

NATURAL NANOPARTICLE-MEDICINE COMPOSITION FOR TREATING ALZHEIMER'S DISEASE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

机译:用于治疗阿尔茨海默病的天然纳米粒子药物组合物,其制备方法及其应用

摘要

The present invention belongs to the field of medicinal preparations, and more particularly relates to preparation and application of a natural nanoparticle-drug composition for Alzheimer's disease (AD) therapy. A technical problem solved by the present invention is to construct the natural nanoparticle-drug composition by extracting natural lipoprotein nanoparticles and recombining AD treatment drugs to achieve the purpose of anti-AD combination treatment. The present invention provides a prescription composition, a preparation process, property evaluation and application of the natural nanoparticle-drug composition, the natural nanoparticle-drug composition is administered in modes of intravenous injection, oral administration, nasal administration and the like, new ideas and new technologies are provided for research and development of new AD drugs, and important research value and clinical research prospects are achieved.
机译:本发明属于药用制剂领域,更具体地涉及用于alzheimer疾病(AD)治疗的天然纳米颗粒 - 药物组合物的制备和应用。本发明解决的技术问题是通过提取天然脂蛋白纳米颗粒和重组AD处理药物来构建天然纳米颗粒 - 药物组合物,以达到抗AD组合处理的目的。本发明提供一种处方组合物,制备方法,自然纳米颗粒 - 药物组合物的制备方法,性质评价和应用,本发明的天然纳米颗粒 - 药物组合物以静脉注射,口服给药,鼻给药等的方式施用,新的想法和提供了新的技术,用于研究和开发新的AD药物,实现重要的研究价值和临床研究前景。

著录项

  • 公开/公告号US2021220288A1

    专利类型

  • 公开/公告日2021-07-22

    原文格式PDF

  • 申请/专利权人 CHINA PHARMACEUTICAL UNIVERSITY;

    申请/专利号US201816755306

  • 发明设计人 JIANPING ZHOU;YANG DING;HUAQING ZHANG;

    申请日2018-11-29

  • 分类号A61K9/51;A61K31/445;A61K31/12;A61K31/4748;A61K31/7105;A61K38/08;A61K31/13;A61K31/5415;

  • 国家 US

  • 入库时间 2022-08-24 20:04:21

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