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SYSTEM AND METHOD FOR QUANTITATIVE DOSIMETRY OF PHOTODYNAMIC THERAPY IN SKIN
SYSTEM AND METHOD FOR QUANTITATIVE DOSIMETRY OF PHOTODYNAMIC THERAPY IN SKIN
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机译:皮肤上光动力疗法定量剂量测定的系统和方法
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摘要
While clinical treatment of actinic keratosis by photodynamic therapy (PDT) is widely practiced, there is well-known variability in response, primarily caused by heterogeneous accumulation and PDT-induced photobleaching of the photosensitizer protoporphyrin IX (PpIX) between patients and between lesions. One of the key factors in regularizing this treatment would be to have an easily accessible indicator of PpIX present in the lesions at the time of light delivery. Described herein, a smartphone-based fluorescence imager was developed to allow simple quantitative photography of the lesions and their PpIX levels.
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