ULTRA-SMALL SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES

摘要

The invention relates to a method for producing an adjusted nanoparticle composition comprising ultra-small superparamagnetic iron oxide nanoparticles coated with dextran-T10, compositions obtained thereby, and uses of such compositions. The adjusted compositions have improved parameters such as lower batch-to-batch variance and improved stability, and are useful as magnetic imaging agents.