首页>
外国专利>
A METHOD OF ENGINEERING NATURAL KILLER CELLS TO TARGET CD70-POSITIVE TUMORS
A METHOD OF ENGINEERING NATURAL KILLER CELLS TO TARGET CD70-POSITIVE TUMORS
展开▼
机译:一种工程天然杀伤细胞的方法,靶向CD70阳性肿瘤
展开▼
页面导航
摘要
著录项
相似文献
摘要
Embodiments of the disclosure include methods and compositions related to targeting of CD70-expressing cells with NK cells specifically engineered to bind the CD70 antigen. In particular embodiments, NK cells that are manipulated to expressing CD70-targeting engineered receptors, such as CARs, are utilized to target cancers that express CD70. In certain embodiments, vectors that express the CD70-targeting CARs also express particular a suicide gene and/or one or more particular cytokines.
展开▼