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SKIN SENSITIZATION MEASURING METHOD AND SKIN SENSITIZATION MEASURING REAGENT

机译:皮肤敏感测量方法和皮肤敏化测量试剂

摘要

An object of the present invention is to provide a method for determining skin allergenicity of a mixture containing two or more test substances, and a reagent for determining the skin allergenicity. The present invention provides a method for determining skin allergenicity, the method including causing a reaction between an organic compound that has at least one thiol group or amino group and emits fluorescence, and a mixture containing two or more test substances, and determining an amount of the organic compound after the reaction or an amount of a product of the reaction by an optical measurement using a fluorescence detector; and a reagent for determining skin allergenicity, the reagent including, as a measurement basis, an organic compound that has at least one thiol group or amino group and emits fluorescence, and being used for determining skin allergenicity of a mixture containing two or more test substances by an optical measurement using a fluorescence detector.
机译:本发明的一个目的是提供一种确定含有两个或更多个测试物质的混合物的皮肤过敏性的方法,以及用于确定皮肤过敏性的试剂。本发明提供了一种用于确定皮肤过敏性的方法,该方法包括导致具有至少一个硫醇基或氨基的有机化合物之间的反应并发射荧光,以及含有两种或多种测试物质的混合物,并确定量反应后的有机化合物或通过使用荧光检测器的光学测量的反应量的产物的量;和一种用于确定皮肤过敏性的试剂,试剂包括作为测量基础,其具有至少一种硫醇基或氨基的有机化合物并发射荧光,并用于确定含有两种或更多种测试物质的混合物的皮肤过敏性通过使用荧光检测器进行光学测量。

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