Composition for preventing or treating inflammatory diseases and cancer, including Hibiscus syriacus leaf callus extract as an active ingredient

摘要

The present invention relates to an anti-inflammatory or anticancer pharmaceutical composition of a callus extract from Mugunghwa leaf, and by culturing the callus separated from Mugunghwa leaf and extracting it, effectively cell proliferation and cell migration in the human colon cancer cell line HT-29 cell line. It was confirmed that the apoptosis factor Bax/Bcl-2 expression ratio and the expression of cytochrome c, caspase-9 and caspase-3 were effectively inhibited, so that the callus extract of Mugunghwa leaf of the present invention was effectively used as an anti-inflammatory or anti-cancer therapeutic agent. It was confirmed that it can be used.