首页> 外国专利> HIGHLY WATER-SOLUBLE SALTS OF A SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKER AND USES THEREOF

HIGHLY WATER-SOLUBLE SALTS OF A SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKER AND USES THEREOF

机译：短暂的苯基烷基胺钙通道阻断剂的高度水溶性盐及其用途

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摘要

The present invention includes surprisingly water-soluble salts of a phenylalkylamine compound that are potent antagonists of L-type calcium channels. Aqueous solutions including salts of the instant invention are formulated for nasal administration and provide a novel therapeutic platform for the treatment of stable angina, migraine, and cardiac arrhythmia, such as paroxysmal supraventricular tachycardia.

机译：本发明包括苯基烷基胺化合物的令人惊讶的水溶性盐，其是L型钙通道的有效拮抗剂。包括本发明的盐的水溶液配制用于鼻给药，并为治疗稳定的心绞痛，偏头痛和心律失常提供新的治疗平台，例如阵发性髁状心动过速。

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公开/公告号US2021205258A1

专利类型
公开/公告日2021-07-08

原文格式PDF
申请/专利权人 MILESTONE PHARMACEUTICALS INC.;
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申请/专利号US202117205726
发明设计人 MARTIN P. MAGUIRE;
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申请日2021-03-18
分类号A61K31/277;A61K9/08;C07C255/42;A61K9;A61K47/12;A61K47/18;A61K47/20;A61P9/10;A61P9/06;A61P25/06;A61K47/02;A61K47/10;A61K47/26;
国家 US
入库时间 2022-08-24 19:46:59

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