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Hybrid Thymus, Methods of Making, and Methods of Using to Induce Xenograft Tolerance, Restore Immunocompetence and Thymic Function
Hybrid Thymus, Methods of Making, and Methods of Using to Induce Xenograft Tolerance, Restore Immunocompetence and Thymic Function
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机译:杂交胸腺,制剂方法和使用方法诱导异种移植耐受性,恢复免疫功能性和胸腺功能
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摘要
The present disclosure relates to making a hybrid pig-human thymic tissue and using the hybrid thymic tissue to induce tolerance in xenotransplantation. The hybrid thymic tissue can also be used for restoring or inducing immunocompetence in a recipient as well as restoring or promoting thymus-dependent ability for T cell progenitors to develop into mature functional T cells in a recipient.
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