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Formulation for bispecific T-cell engagers (BiTEs)
Formulation for bispecific T-cell engagers (BiTEs)
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机译:双特异性T细胞收纳的配方(咬伤)
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摘要
The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen-binding domains and are especially suited for subcutaneous administration. The invention provides liquid compositions which minimize the formation of undesired polypeptide aggregates (dimers and/or multimers). The present invention further provides a method for minimizing the aggregation of polypeptides having antigen-binding domains in liquid compositions.
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