首页> 外国专利> Pyrimidine derivative compound, optical isomer thereof, or pharmaceutically acceptable salt thereof, and composition for preventing or treating Tyro 3 related disease comprising same as active ingredient

Pyrimidine derivative compound, optical isomer thereof, or pharmaceutically acceptable salt thereof, and composition for preventing or treating Tyro 3 related disease comprising same as active ingredient

机译:嘧啶衍生物化合物,其光学异构体,或其药学上可接受的盐,以及用于预防或治疗包含与活性成分相同的Tyro 3相关疾病的组合物

摘要

A pyrimidine derivative compound of Chemical Formula 1, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating cancer comprising the same as an active ingredient. The pyrimidine derivative compound of Chemical Formula 1, the optical isomer thereof, or the pharmaceutically acceptable salt thereof has an excellent selective inhibitory effect especially against TYRO 3 among TAM receptor inhibitory effects, and thus can be used as an excellent composition of preventing or treating cancer without adverse effects resulting from the inhibition of Axl and Mer.; embedded image
机译:化学式1,其光学异构体或其药学上可接受的盐的嘧啶衍生物化合物,以及用于预防或治疗包含与活性成分相同的癌症的组合物。化学式1的嘧啶衍生物,其光学异构体或其药学上可接受的盐具有优异的选择性抑制作用,特别是在TAM受体抑制作用中抗Tyro 3,因此可以用作预防或治疗癌症的优异组成没有抑制AXL和MER产生的不利影响; <化学ID =“Chem-US-00001”> “嵌入式图像”文件=“US11053225-20210706-C00001.gif”他=“30.56mm”ImgContent

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