首页>
外国专利>
Anti-cd79b antibody and immunosuppressant and their application
Anti-cd79b antibody and immunosuppressant and their application
展开▼
机译:抗CD79B抗体和免疫抑制剂及其应用
展开▼
页面导航
摘要
著录项
相似文献
摘要
FIELD: medicine.;SUBSTANCE: present group of inventions relates to biotechnology. What is presented is a humanised anti-CD79b antibody and its antigen-binding fragment produced of murine antibody MA79b and CD79b having a substantially analogous binding affinity thereto. A polynucleotide, a vector, a host cell and a method for producing the anti-CD79b antibody according to the invention; immunoconjugates, compositions and methods for cell growth inhibition, a method of treating an individual suffering cancer, a method of treating a proliferative disease and tumour in a mammal, a method for B-cell proliferation inhibition; a method for detecting the presence of CD79b in a sample and method for binding the antibody to the CD79b expressing cell are also disclosed.;EFFECT: given invention can find further application in therapy of the CD79b associated diseases.;86 cl, 20 tbl, 9 ex, 51 dwg
展开▼