LATERAL FLOW ASSAYS COMPRISING NON-SPHEROIDAL GOLD NANOPARTICLES

摘要

Spherical gold nanoparticles are the most used label in lateral flow test devices because it is easy to conjugate biological molecules onto gold nanoparticles, they have a strong red color and they are relatively stable. However, there is a need to improve the sensitivity of lateral flow devices to decrease their lower detection limit. The present invention aims to improve the sensitivity of lateral flow devices by using nanoparticles having a substantially polyhedron shape and stronger plasmon/color.