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A composition for the prevention, improvement or treatment of sleep disorders containing Curcuma longa extract

机译:用于预防,改进或治疗含有Curcuma Longa提取物的睡眠障碍的组合物

摘要

The present invention relates to a composition for preventing, improving or treating sleep disorders containing a turmeric extract as an active ingredient. The turmeric extract of the present invention provides the effect of reducing the waking time, increasing the duration of sleep and increasing non-REM sleep at almost the same level or improved level as redolmin or diazepam, which are drugs used as conventional sleep inducing agents. In addition, the turmeric extract of the present invention suppresses the sleep effect in the same way that the sleep effect of pyrylamine maleate salt, known as a conventional histamine receptor antagonist, is completely inhibited by 2-pyridylethylamine dihydrochloride, a histamine receptor agonist, Acts as a natural antihistamine. In addition, since it is derived from turmeric, which is a natural product, there is no side effect of forming cognitive impairment, tolerance or dependence even after long-term use. Therefore, the composition for preventing, improving or treating sleep disorders comprising the turmeric extract of the present invention as an active ingredient is very useful in the preparation of competitive food compositions and pharmaceutical compositions.
机译:本发明涉及用于预防,改善或治疗含有姜黄提取物作为活性成分的睡眠疾病的组合物。本发明的姜黄提取物提供了减少唤醒时间的效果,增加睡眠持续时间,并且在几乎与yedolmin或Diazepam的几乎相同或改善的水平上增加非REM睡眠,这是用作常规睡眠诱导剂的药物。此外,本发明的姜黄提取物以相同的方式抑制睡眠效果,使得称为常规组胺受体拮抗剂的钙酰胺马来酸盐的睡眠作用完全抑制2-吡啶基乙胺二盐酸盐,组胺受体激动剂,作用作为天然抗组胺药。此外,由于它是姜黄,即是天然产品的姜黄,即使在长期使用之后也没有形成认知障碍,耐受性或依赖性的副作用。因此,用于预防,改善或治疗包含本发明姜黄提取物作为活性成分的睡眠障碍的组合物在制备竞争性食品组合物和药物组合物中非常有用。

著录项

  • 公开/公告号KR102262752B1

    专利类型

  • 公开/公告日2021-06-10

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020190130749

  • 申请日2019-10-21

  • 分类号A61K36/9066;A23K10/30;A23L33/105;A61K31/12;A61P25/20;

  • 国家 KR

  • 入库时间 2022-08-24 19:16:57

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