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METHOD FOR DETERMINING PROBABILITY OF ISCHEMIC HEART DISEASE IN YOUNG PATIENTS WITH ABDOMINAL OBESITY

机译:腹部肥胖患者缺血性心脏病概率确定缺血性心脏病概率的方法

摘要

FIELD: medicine; cardiology.;SUBSTANCE: invention relates to the field of medicine, namely to cardiology, and concerns a method for determining the presence of ischemic heart disease (hereinafter – IHD) in young patients aged 25-44 years with abdominal obesity. In the patient’s blood serum, the concentration of leptin, adipsin and visphatin is determined, the values obtained are compared with the threshold value of the corresponding biomarker, equal to 3600 pg/ml for leptin, 4.2 mcg/ml for adipsin, and 8 ng/ml for visphatin. If at least two biomarker values deviate from the threshold values, a conclusion is made about the presence of ischemic heart disease in a young patient aged 25-44 years with abdominal obesity. At the same time, for leptin and adipsin, an increase in the concentration relatively to the threshold value is considered a deviation, and for visfatin, a decrease in the concentration relatively to the threshold value is considered a deviation. ;EFFECT: invention provides for the creation of a non-invasive, affordable and inexpensive biochemical method for determining the probability of IHD in young patients with abdominal obesity, which can be used for effective early diagnostics.;1 cl, 2 tbl, 3 ex
机译:领域:医学;心脏病学。物质:发明涉及医学领域,即心脏病学,涉及在腹部肥胖症25-44岁的年轻患者中确定缺血性心脏病(下文中)存在的方法。在患者的血清中,测定瘦蛋白,副素和静液的浓度,与相应的生物标志物的阈值进行比较,相当于瘦素,4.2mcg / ml的3600pg / ml,以及8 ng / ml用于粘膜。如果至少两个生物标志物值偏离阈值,则在腹部肥胖症25-44岁的年轻患者中存在缺血性心脏病存在的结论。同时,对于瘦素和副尖,相对于阈值的浓度的增加被认为是偏差,并且对于visfatin,相对于阈值的浓度的降低被认为是偏差。 ;效果:发明提供了用于在腹部肥胖患者中确定IHD概率的非侵入性,实惠且廉价的生化方法,可用于有效的早期诊断。; 1 cl,2 tbl,3前

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