NANOLIPOSOME CONTAINING LUTEIN AND CORDYCEPS MILITARIS ALCOHOL EXTRACT, AND METHOD FOR PREPARATION THEREOF

摘要

Provided are a nanoliposome containing lutein and Cordyceps militaris alcohol extract, and a method for preparation thereof; the contained amount of Cordyceps militaris alcohol extract is 4%–8% by mass, and the mass ratio of lutein to Cordyceps militaris alcohol extract is 1:3–1:5. An ethanol injection method is combined with micro-jet technology to achieve co-loading of lutein and Cordyceps militaris alcohol extract, two active substances having different hydrophobicities, in a nanoliposome; the prepared liposome has a particle size of less than 200 nm, the loading rate of lutein is higher than 90%, the loading rate of Cordyceps militaris alcohol extract is higher than 85%, and stability is good; the preparation process is safe and simple, costs are low, facilitating industrial production.