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Suspension Cell Culture Adapted Vaccine Strain Derived from Foot-and-mouth disease virus of A/ASIA/Sea-97 Lineage and Method of Preparing the Same
Suspension Cell Culture Adapted Vaccine Strain Derived from Foot-and-mouth disease virus of A/ASIA/Sea-97 Lineage and Method of Preparing the Same
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机译:悬浮细胞培养适应疫苗菌株源自A /亚海/海-97谱系的口蹄疫病毒和制备方法的方法
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摘要
The present invention relates to an A/ASIA/Sea-97 genotype foot-and-mouth disease virus vaccine line adapted for floating cell culture, a foot-and-mouth disease virus vaccine composition comprising the same, and a method for preparing the same, and more particularly, to A/ASIA/Sea-97 genotype. It relates to a foot-and-mouth disease virus vaccine line in which cell adaptability was established by alternately subcultures in adherent cells and suspended cells of foot-and-mouth disease virus, a vaccine composition comprising the inactivated virus vaccine line as an active ingredient, and a method for producing the same.
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机译:本发明涉及一种适用于浮动细胞培养物的A /亚海/海-97基因型患者疫苗疫苗疫苗,其包含相同的脚口病病毒疫苗组合物,以及制备该步骤,更具体地,对A / ASIA / SEA-97基因型。它涉及一种口蹄疫病毒疫苗系,其中通过在粘附细胞和口蹄疫病毒的悬浮细胞和悬浮细胞中交替地建立细胞适应性,疫苗组合物包含灭活病毒疫苗系作为活性成分以及制造该方法的方法。
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