SYNERGISTIC COMBINATION OF BUTYRIC-ACID-PRODUCING PREBIOTICS AND PROBIOTICS

摘要

Provided is a synergistic combination of butyric-acid-producing prebiotics and probiotics, which is used in the fields of foods, dietary supplements and drugs. Specifically, the present invention relates to a composition containing probiotics and prebiotics, a food, dietary supplement or pharmaceutical preparation comprising the composition, and the use of the composition for alleviating and improving a disease or a discomfort, or reducing the occurrence of a disease or a discomfort, wherein the disease or discomfort is related to insufficient butyric acid in the intestine, or to insufficient butyric-acid-producing microorganisms in the intestine. The present invention further relates to a method for promoting Bifidobacterium lactis HN019 to produce butyric acid, the method comprising using a galactooligosaccharide and isomerized lactose as carbon sources for the cultivation of Bifidobacterium lactis HN019, wherein the weight ratio of the galactooligosaccharide to isomerized lactose is 1:1 to 4:1.