METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR ENHANCED VIRTUAL CROSSMATCHING USING PHYSICAL-CROSSMATCH-OUTCOME-DATA-DERIVED MODEL

摘要

A method for virtual crossmatching using a physical-crossmatch-outcome-data-derived model includes receiving as inputs, human leukocyte antigen (HLA) antibody mean fluorescence intensity (MFI) data of a prospective tissue recipient and HLA typing data of a tissue donor. The method further includes generating, based on the inputs and a physical-crossmatch-outcome-data-derived model, a predicted virtual crossmatch outcome for the prospective tissue recipient. The method further includes using the predicted virtual crossmatch outcome to inform a transplant decision for the prospective tissue recipient.