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A novel peptide and peptide combination for use in immunotherapy and methods for preparing scaffolds for use in pancreatic cancer and other cancers

机译:用于免疫疗法的新型肽和肽组合及其制备用于胰腺癌和其他癌症的支架的方法

摘要

Problem to be solved: to provide a novel peptide sequence derived from HLA class I molecules of human tumor cells and their variants in vaccine compositions for inducing antitumor immune responses or as targets for the development of pharmacological / immunological active compounds and cells.A peptide comprising a specific amino acid sequence that can be recognized by CD4 and / or CD8 T cells if it has the ability to bind to MHC class I or II molecules and binds to the MHC class I or II molecule Or provide a pharmaceutically acceptable salt thereof.No selection
机译:要解决的问题:提供一种新的肽序列,其衍生自人肿瘤细胞的HLA A类分子及其在疫苗组合物中的变体,用于诱导抗肿瘤免疫应答或作为发育药理学/免疫活性化合物和细胞的靶标。包含特定氨基酸序列的肽,其可以通过CD4和/或CD8 T细胞识别,如果能够与MHC I类或II分子结合并与MHC I类或II分子结合或提供药学上可接受的盐它。没有选择

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