METHODS AND SYSTEMS FOR IMPROVING THE RELIABILITY OF ORTHOGONALLY REDUNDANT GLUCOSE SENSORS

摘要

Methods and systems for sensor calibration and sensor glucose (SG) fusion are advantageously used to improve the accuracy and reliability of orthogonal redundant glucose sensor devices, and such sensor devices may include optical and electrochemical glucose sensors. Calibration for both sensors can be achieved through fixed-offset and/or dynamic regression methodologies, for example depending on sensor stability and Isig-ratio pair correlation. For SG fusion, individual integrity checks can be performed on SG values from optical and electrochemical sensors, and if the integrity checks pass, the SG values are calibrated. Integrity check may include checking for loss of sensitivity, noise, and drift. If the integrity checks fail, inline sensor mapping between electrochemical and optical sensors can be performed prior to calibration. The electrochemical and optical SG values can be weighted (as a function of the overall reliability index (RI) of each sensor), and the weighted SGs are combined to obtain a single, fused SG value.