A SOLUBLE FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGR3) POLYPEPTIDE FOR USE IN THE PREVENTION OR TREATMENT OF SKELETAL GROWTH RETARDATION DISORDERS

摘要

The present invention relates to the prevention of skeletal growth retardation diseases, in particular skeletal diseases, caused by patients exhibiting abnormally increased activation of fibroblast growth factor receptor 3 (FGFR3), in particular by expression of prolonged activated mutants of FGFR3 or It's about treatment. More particularly, the present invention relates to soluble FGFR3 for use in the prevention or treatment of achondroplasia.