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CUSTOMAZIBLE 3D CELL CULTURE SYSTEM COMPRISING HYDROGEL-EMBEDDED CELLS AND USES THEREOF

机译:包含水凝胶嵌入电池的可定制的3D细胞培养系统及其用途

摘要

A three-dimensional (3D) cell culture system comprising: a solid porous polymeric support, preferably comprising a biocompatible polymer; a first type of cells bound to the solid porous polymeric support; and a biocompatible hydrogel comprising a second type of cells, wherein biocompatible hydrogel is in physical contact with the solid porous polymeric support, is described. Methods for preparing this 3D cell culture system, as well as uses of this system for example for anticancer drug screening, are also described.
机译:三维(3D)细胞培养系统,包括:固体多孔聚合物载体,优选包含生物相容性聚合物;一种与固体多孔聚合物载体结合的第一类细胞;和一种包含第二种细胞的生物相容性水凝胶,其中,描述了生物相容性水凝胶与固体多孔聚合物载体物理接触。还描述了制备该3D细胞培养系统的方法,以及例如用于抗癌药物筛选的该系统的用途。

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