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METHOD AND APPARATUS FOR SELECTING NEW DRUG REPURPOSING CANDIDATE

机译:选择新药重新扫描候选者的方法和装置

摘要

A method by which a new drug repurposing candidate selection apparatus selects a new drug repurposing candidate, in one embodiment, comprises the steps of: acquiring, within a predetermined period range, clinical indicator values obtained before/after exposure to predetermined drugs for each of a plurality of patients; calculating a change in the clinical indicator values obtained before/after exposure to the predetermined drugs for each acquired clinical indicator; calculating the total number of exposed drugs by including the predetermined drugs for each of the plurality of patients; correcting the calculated change for each of the plurality of patients by using the total number of calculated drugs or weight per drug; determining, on the basis of the corrected change, effects that exclude the predesignated effects of the predetermined drug; and acquiring a ranking for having a high probability of new drug repurposing by using, individually, or combining the effects of the drugs.
机译:在一个实施例中,新药物重新扫描候选选择装置选择新药物重新扫描候选的方法包括以下步骤:获取,在预定时段范围内,在暴露于每一个的预定药物之前/之后获得的临床指示值。多个患者;计算在暴露于每次获得的临床指标之前/之后获得的临床指示剂值的变化;通过包括多个患者中的每一个的预定药物计算暴露药物的总数;通过使用每种药物的计算药物或重量的总数校正多个患者中的每一个的计算变化;基于校正的变化,确定排除预定药物的预测效果的效果;并获得通过使用药物单独或组合药物的影响的新药物重新施加的概率的排名。

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