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EPHA3 DIRECTED CAR-T CELLS FOR TREATMENT OF TUMORS
EPHA3 DIRECTED CAR-T CELLS FOR TREATMENT OF TUMORS
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机译:EphA3定向Car-T细胞用于治疗肿瘤
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摘要
This invention provides chimeric antigen receptors (CARs) targeting human EphA3 and dual targeting CARs that bind to human EphA3 and to human mutant epidermal growth factor receptor variant III (EGFRvIII). This invention also relates to CAR-T cells comprising the provided CARs or the dual targeting CARs. Methods for treating a solid tumor cancer by administering the CARs are provided.
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