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BLOOD PLATELET INHIBITION RATE CALCULATION METHOD BASED ON THROMBOELASTOGRAM

机译:基于血栓弹跳的血小板抑制率计算方法

摘要

A blood platelet inhibition rate calculation method based on a thromboelastogram. The method comprises: testing a blood sample to obtain a thromboelastogram, wherein the thromboelastogram comprises a maximum coagulation intensity MAt curve, a minimum coagulation intensity MAf curve and a blood platelet coagulation curve f(t) after the blood sample coagulates; transforming coordinate axes of the curves of the thromboelastogram, and translating an X axis to the position of a symmetry axis of the three curves; integrating a numerical amplitude value of a coagulation intensity that is obtained by testing, and a coagulation time value, and respectively calculating an integral coagulation intensity DIt of the maximum coagulation intensity MAt curve, an integral coagulation intensity DIf of the minimum coagulation intensity MAf curve, and an integral coagulation intensity DI of the coagulation curve f(t); and calculating a blood platelet inhibition rate BPI = (1 - (DI - DIf)/(DIt - DIf)) × 100%. An evaluation result obtained by means of the calculation method is more accurate and can correctly reflect the actual state in which blood platelets are inhibited after the use of a blood platelet inhibition drug.
机译:一种基于血栓弹跳的血小板抑制率计算方法。该方法包括:测试血液样品以获得血栓抑制图,其中血栓发球图包含最大凝固强度MA T 曲线,最小凝固强度MA F 曲线和血小板血液样品凝固后的凝血曲线F(t);转换旋流图的曲线的坐标轴,并将X轴平移到三条曲线的对称轴的位置;整合通过测试获得的凝固强度的数值幅度值,以及分别计算最大凝固强度MA T T >曲线,最小凝固强度MA 曲线的整体凝固强度DI f 凝固曲线F(t)的整体凝固强度DI;并计算血小板抑制率BPI =(1 - (DI - DI F )/(di t - di f ))×100 %。通过计算方法获得的评估结果更准确,并且可以正确反映在使用血小板抑制药物后抑制血小板的实际状态。

著录项

  • 公开/公告号WO2021077728A1

    专利类型

  • 公开/公告日2021-04-29

    原文格式PDF

  • 申请/专利权人 ZIRCON BIOTECH CO. LTD.;

    申请/专利号WO2020CN90323

  • 发明设计人 LI GANG;FAN ZHIMING;SUO WEI;ZHANG YIFAN;

    申请日2020-05-14

  • 分类号G01N33/86;G16H50;

  • 国家 CN

  • 入库时间 2022-08-24 18:29:50

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