- - Method for high-efficiency conversion of the toxic diester-diterpenoid alkaloids and monoester-diterpenoid alkaloids contained in Aconitum ciliare Decaisne to aconine

摘要

The present invention is a method for converting diester-diterpenoid alkaloids and monoester-diterpenoid alkaloids, which are highly toxic substances contained in Choo, to aconine with high efficiency, and to prepare a non-toxic Choo extract with a high content of aconine using the same. It's about how. According to the unique process method provided by the present invention, the diester-diterpenoid alkaloid and the monoester-diterpenoid component contained in Choo can be converted (converted) to aconine at an almost complete level. This is in contrast to those known by conventional numerical methods that were only effective for converting diester-diterpenoid alkaloids to monoester-diterpenoid alkaloid components (particularly, benzoylaconine).According to the present invention, benzoyl aco Non-toxic Choo extract (processed product) containing high aconine, which is superior to nin in terms of pharmacology and safety, can be prepared.