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Two periodontal ligament progenitor cell surface specific IgG type monoclonal antibodies LG43, LG73 and uses thereof

机译:两个牙周韧带祖细胞表面特异性IgG型单克隆抗体LG43,LG73及其用途

摘要

The present invention relates to two IgG type monoclonal antibodies LG43 and LG73 that specifically bind to the surface of periodontal ligament progenitor cells, and to their use, specifically binding to the surface of periodontal ligament progenitor cells of the present invention. When using an IgG monoclonal antibody, periodontal ligament progenitor cells that can be usefully used for tissue regeneration and differentiation can be effectively isolated and purified, and the IgG monoclonal antibody effectively differentiates periodontal ligament stem cells into periodontal ligament progenitor cells. It can also be usefully used for screening of substances that promote it.
机译:本发明涉及两种IgG型单克隆抗体LG43和LG73,其特异性结合到牙周韧带祖细胞的表面,以及它们的使用,特别是与本发明的牙周韧带祖细胞的表面结合。当使用IgG单克隆抗体时,可以有效地分离和纯化可以有效地用于组织再生和分化的牙周韧带祖细胞,并且IgG单克隆抗体有效地将牙周韧带干细胞与牙周韧带祖细胞分化。它也可以用来用于筛选促进它的物质。

著录项

  • 公开/公告号KR102245082B1

    专利类型

  • 公开/公告日2021-04-26

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020200018151

  • 发明设计人 장영주;배상훈;

    申请日2020-02-14

  • 分类号C07K16/28;C12N5/077;G01N33/569;

  • 国家 KR

  • 入库时间 2022-08-24 18:27:34

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