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Antibody constructs against CLDN18.2 and CD3

机译:针对CLDN18.2和CD3的抗体构建体

摘要

The present invention relates to antibody constructs comprising a domain that binds Claudin 18.2 (CLDN18.2) and another domain that binds CD3. In addition, the present invention provides a polynucleotide encoding an antibody construct, a vector comprising the polynucleotide, and a host cell transformed or transfected with the polynucleotide or vector. Furthermore, the present invention provides a method for producing the antibody construct of the present invention, a medical use of the antibody construct, and a kit comprising the antibody construct.
机译:本发明涉及抗体构建体,其包含结合ClaudIn 18.2(CLDN18.2)和结合CD3的另一个结构域的结构域。另外,本发明提供了编码抗体构建体的多核苷酸,含有多核苷酸的载体,以及用多核苷酸或载体转化或转染的宿主细胞。此外,本发明提供了制备本发明的抗体构建体的方法,抗体构建体的医学用途,以及包含抗体构建体的试剂盒。

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