LYOPHILIZED PREPARATION OF STEM CELL-DERIVED EXOSOMES, AND ANTI-INFLAMMATORY COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT

摘要

The present invention provides a lyophilized formulation of stem cell-derived exosomes used for the prevention, suppression, alleviation, amelioration or treatment of inflammation, and an anti-inflammatory composition including the same as an active ingredient. The lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient according to the present invention is able to stabilize stem cell-derived exosomes and exhibit excellent anti-inflammatory effects, and particularly, exhibit remarkable anti-inflammatory effects as compared with not-lyophilized stem cell-derived exosomes isolated and purified from conditioned media of stem cells. Therefore, the lyophilized formulation of stem cell-derived exosomes and the anti-inflammatory composition including the same as an active ingredient is able to effectively prevent, suppress, alleviate, ameliorate or treat inflammatory response or inflammatory diseases.