An infant formula for use in reducing the occurrence of, or preventing, an infection in an infant, wherein the infant formula is an extensively hydrolysed infant formula (eHF) or an amino acid- based infant formula (AAF), wherein the infant formula comprises protein, carbohydrate and fat, wherein the eHF comprises about 2.4 g or less protein per 100 kcal, or the AAF comprises about 2.9g or less protein per 100kcal, wherein the infant formula further comprises 2'- fucosyllactose (2'FL) and/or lacto-N-neotetraose (LNnT), and wherein about 30% or less by weight of the fat is medium chain triglycerides (MCTs).
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