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PHARMACEUTICAL COMPOSITIONS FOR TREATING EBOLA VIRUS DISEASE
PHARMACEUTICAL COMPOSITIONS FOR TREATING EBOLA VIRUS DISEASE
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机译:用于治疗埃博拉病毒病的药物组合物
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摘要
The present invention provides compounds and pharmaceutical compositions adapted to reduce a load of an RNA virus by at least 50%, the virus causing a pathogenic disease in a mammalian subject, the compound adapted to inhibit the formation of S-adenosyl methionine (SAM) in the virus, the compound being a DOTIL inhibitor, wherein the compound has a molecular weight of less than 1000, and a therapeutic index (TI=LD.sub.50:ED.sub.50) greater than 30 in the mammalian subject.
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