INCREASING IMMUNE ACTIVITY THROUGH MODULATION OF POSTCELLULAR SIGNALING FACTORS

摘要

The invention provides methods of increasing immune response by inducing iron- dependent cellular disassembly. The increase in immune response may be used, for example, for treatment of infection or cancer. The invention also provides screening assays for identification of compounds that induce iron-dependent cellular disassembly and are also immuno stimulatory agents. The invention further provides methods for identifying immuno stimulatory agents produced by cells undergoing iron-dependent cellular disassembly.