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Method for treating obesity and non alcoholic fatty liver disease or non alcoholic steatohepatitis using glucagon receptor antagonist antibody

机译:使用胰高血糖素受体拮抗剂抗体治疗肥胖和非酒精脂肪肝疾病或非酒精脂肪肝炎的方法

摘要

The present disclosure relates to methods for treating or preventing obesity and / or nonalcoholic fatty liver disease (NAFLD) and / or nonalcoholic steatohepatitis (NASH) using a glucagon receptor blocker. In various embodiments, the present disclosure provides for treating or preventing NAFLD / NASH using antagonistic antigen binding proteins, such as fully human antibodies, that specifically bind to and antagonize the function of the human glucagon receptor. Regarding the method. [Selection] Figure 3
机译:本公开涉及使用胰高血糖素受体阻滞剂治疗或预防肥胖和/或非酒精脂肪肝疾病(NAFLD)和/或非酒精性脂肪肝炎(NASH)的方法。在各种实施方案中,本公开内容提供了使用拮抗抗原结合蛋白治疗或预防NAFLD / NASH,例如完全人体抗体,其特异性结合并拮抗人胰血糖素受体的功能。关于方法。 [选择]图3

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