Alzheimer's disease is a senile disease in which the main clinical features are progressive memory impairment, judgment and reasoning impairment, and movement impairment. The pathological manifestation of Alzheimer's disease is a degenerative process of the nervous system characterized by diffuse brain atrophy, and a degenerative process related to the inflammatory response of brain tissue. Therefore, down-regulating inflammatory cytokines and inhibiting inflammatory response can be an important means to improve the pathological basis and clinical symptoms of Alzheimer's disease. By conducting Morris water maze tests on experimental rats and measuring the inflammatory cytokines in the brain tissue thereof, an Elapidae snake postsynaptic neurotoxin monomer molecule was found to inhibit the inflammatory cytokines in the brain tissue of rats with senile dementia and improve the learning and memory ability of the rats with senile dementia, providing a possibility for the application of the Elapidae snake postsynaptic neurotoxin monomer molecule in the treatment of senile dementia.
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