首页> 外国专利> CHEMILUMINESCENCE SUBSTRATE HAVING HIGH LUMINESCENCE INTENSITY, LONG WAVELENGTH, AND GOOD STABILITY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

CHEMILUMINESCENCE SUBSTRATE HAVING HIGH LUMINESCENCE INTENSITY, LONG WAVELENGTH, AND GOOD STABILITY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

机译:化学发光底物具有高发光强度,长波长和良好的稳定性,以及其制备方法及其应用

摘要

The invention provides a chemiluminescence substrate having high luminescence intensity, a long wavelength, and good stability, and a preparation method therefor and an application thereof. The chemiluminescence substrate has a structure represented by formula I. In addition, the present invention provides an autofluorescence wavelength and intensity of a chemiluminescence probe in a physiological environment and an application of the chemiluminescence probe in living imaging. Testing results show that the chemiluminescence probe provided by the present invention has autofluorescence of a long wavelength (600 nm), is capable of effectively penetrating a skin tissue, and has high autofluorescence intensity (greater than 107 p/s/cm2/sr), excellent thermal stability (without 1,2-dioxetane structure), and diverse detection groups (applicable to different detection models).
机译:本发明提供一种具有高发光强度,长波长和良好稳定性的化学发光底物,以及其制备方法及其应用。化学发光底物具有由式I表示的结构。此外,本发明提供了生理环境中的化学发光探针的自发荧光波长和强度,并在生物成像中的应用。测试结果表明,本发明提供的化学发光探针具有长波长(600nm)的自发荧光,能够有效地穿透皮肤组织,并且具有高的自发荧光强度(大于10 7 p / s / cm 2 / sr),优异的热稳定性(没有1,2-二氧杂环丁烷结构)和不同的检测组(适用于不同的检测模型)。

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