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MAGNETIC PARTICLE LUMINESCENCE MICRO-FLUIDIC CHIP FOR MULTI-MARKER DETECTION, AND DETECTION DEVICE

机译:用于多标记检测的磁颗粒发光微流体芯片和检测装置

摘要

Disclosed are a magnetic particle luminescence micro-fluidic chip for multi-marker detection, and a detection device, belonging to the technical field of micro-fluidic chip luminescence immunodetection. The magnetic particle luminescence micro-fluidic chip comprises: a top plate (1), wherein the top plate (1) is provided with a sample adding part (11), a mixing area (12) and a plurality of marking ligands arranged in the mixing area (12); a bottom plate (2), wherein the bottom plate (2) comprises a flow guide area (21), a plurality of reaction areas (22), a plurality of detection areas in communication with the corresponding reaction areas (22), and a cleaning liquid storage part (24) and a luminous liquid storage part (25) in communication with the detection areas, and each reaction area (22) is provided with a magnetic particle ligand, the ligand of each magnetic particle ligand being different, and a cleaning liquid is contained in the cleaning liquid storage part (24), and a luminous liquid is stored in the luminous liquid storage part (25); and an air pump (13), which is arranged on the top plate (1) and used for driving a sample in the sample adding part (11) to flow through the mixing area (12). Due to the fact that the plurality of reaction areas (22) are provided, the phenomenon of cross interference between magnetic particles is avoided, the accuracy of detection results can be greatly improved, there is no requirement for the moving speed of a magnet, and control over the device is facilitated.
机译:公开了一种用于多标记检测的磁颗粒发光微流体芯片,以及属于微流体芯片发光免疫检测技术领域的检测装置。磁颗粒发光微流体芯片包括:顶板(1),其中,顶板(1)设置有样品添加部分(11),混合区域(12)和布置在的多个标记配体。混合区域(12);底板(2),其中底板(2)包括导流区域(21),多个反应区域(22),多个与相应的反应区域(22)连通的检测区域,以及清洁液体储存部分(24)和与检测区域连通的发光液体存储部分(25),并且每个反应区域(22)设置有磁性颗粒配体,每个磁性颗粒配体的配体不同,以及a清洁液体包含在清洁液体储存部分(24)中,发光液体存储在发光液体储存部分(25)中;和一个空气泵(13),其布置在顶板(1)上,并且用于驱动样品加入部分(11)中的样品流过混合区域(12)。由于提供了多个反应区域(22),避免了磁性颗粒之间的交叉干涉的现象,可以大大提高检测结果的精度,没有要求磁铁的移动速度,并且促进对设备进行控制。

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