CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF

摘要

The present invention provides a cyclic peptide that has, in a ring, an amino acid sequence represented by formula (I): X₁-His-Pro-X₄-Leu-X₆-X₇-X₈-Ser-X₁₀-His-Phe (where X₁, X₄, X₆, X₇, X₈, and X₁₀ each independently represent an arbitrarily defined amino acid) and that has an activity of specifically binding to human CTLA-4.