Hybrid hydrogels comprised of decellularized extracellular matrix (dECM) and biocompatible conductive nanomaterials are disclosed. The hybrid hydrogels provide a more instructive microenvironment for proper cell and tissue development. The mechanical and electrical properties of the hydrogels can be tuned. The hydrogels can be used in bioinks for printing tissues in a high-throughput manner, and engineered tissues generated using the hybrid hydrogels can be utilized to assess biological activity of drug candidates.
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