Systems and methods for providing respiratory therapy are disclosed. One device includes a nasal cannula comprising at least at one nasal prong, tubing and a breathing gas conduit. The nasal prong has a proximal tip and a distal end connected to the breathing gas conduit. The breathing gas conduit has an inlet port, an outlet port, and a walled flow path connecting the inlet and outlet ports, such that the conduit directs the breathing gas from the tubing to the proximal tip of the nasal prong. A nebulizer is secured to the nasal cannula and operable to aerosolize a medicament via a vibrating mesh. The vibrating mesh is secured to the nasal cannula and is positioned adjacent to the breathing gas conduit such that the aerosol is entrained with the breathing gas at proximal tip of the nasal prong.
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