ENHANCED STABILITY OF ZINC PYRITHIONE IN OXIDATIVE ENVIRONMENTS, SUCH AS SCALP SEBACEOUS FLUID

摘要

The present invention discloses a personal care composition comprising: (a) A polyvalent metal salt of pyrithione; (b) A metal complex selected from the group consisting of: wherein Y₁, Y₂, Z₁, Z₂ are selected from the following groups: -NH₂, -NHR₁₁, -NR₁₂R₁₂, -NHCO-R₂₀, -SH, -OR₁₃, -O(C=O)-, phosphate. and wherein at least one of Y₁ and Z₁ of compound I is -SH, and wherein at least one of Y₂ and Z₂ of compound II is -SH R₁, R₂, R₃, R₄, R₅, R₆, R₇, R₈, R₉, R₁₀, can independently be H, alkyl, substituted alkyl, phenyl, aryl; R₁₄ is -NH₂, -NHCO-CH₃, -NHR₁₇, or -NR₁₈R₁₈ R15 is -COOH, - COOR₁₉ R₁₁, R₁₂, R₁₃ R₁₆, R₁₇, R₁₈, R₁₉ can be independently be alkyl, substituted alkyl, phenyl, aryl. and wherein the metal of the complex is selected from the group consisting of zinc, copper, and iron.