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UREA DERIVATIVE MODULATORS OF TRYPTOPHAN CATABOLISM

机译:色氨酸分解代谢的尿素衍生调节剂

摘要

There are described compounds of formula (I): (I) and their use as a medicament in the treatment of diseases associated with the abnormal or elevated catabolism of tryptophan, such as, cancer, immunosuppression, viral infection, depression, a neurodegenerative disorder, trauma, age-related cataracts, organ transplant rejection, or an autoimmune disorder in a patient.
机译:描述了式(I)化合物:(i)和它们作为治疗与色氨酸异常或升高分解代谢相关的疾病的药物,例如癌症,免疫抑制,病毒感染,抑郁症,神经变性障碍,创伤,年龄相关的白内障,器官移植抑制,或患者的自身免疫疾病。

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