PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for preventing or treating a metabolic disease, and a method for preventing or treating a metabolic disease using the same. SOLUTION: A novel strain of Akkermansia sp., Which is a kind of intestinal mucin-degrading bacterium isolated from breast milk of a healthy Korean pregnant woman, a vesicle of the strain, a proteome and a metabolite of the strain, A pharmaceutical composition for the prevention or treatment of metabolic diseases, which comprises at least one selected from the group consisting of a culture of the strain, a disrupted product of the strain, and the disrupted product or an extract of the culture as an active ingredient. It is a thing. [Selection diagram] Fig. 1
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