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A DEEP LEARNING FRAME FOR IDENTIFYING SEQUENCE PATTERNS THAT CAUSE SEQUENCE SPECIFIC ERRORS (SSE)
A DEEP LEARNING FRAME FOR IDENTIFYING SEQUENCE PATTERNS THAT CAUSE SEQUENCE SPECIFIC ERRORS (SSE)
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机译:用于识别导致序列特定错误(SSE)的序列模式的深度学习框架
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摘要
FIELD: computing.;SUBSTANCE: invention relates in particular to computers and digital data processing systems related to artificial intelligence. The technical result is achieved by processing the superimposed samples with a convolutional neural network and based on the detection of nucleotide patterns in the superimposed samples by convolutional neural network filters, generating classification scores for the likelihood that the specified variant nucleotide in each of the superimposed samples is a true variant or a false variant; outputting distributions of classification points generated by a pre-trained subsystem of the filter of options for the repetition factors of the corresponding repeating patterns; and indicating, based on the threshold, a subset of classification scores in said distributions as indicating false classifications of variants and classifications of repetitive patterns that are associated with this subset of classification scores that indicate false classifications of variants as causing sequence-specific errors.;EFFECT: technical result consists in minimizing training errors of the convolutional neural network.;25 cl, 21 dwg
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