SCHISTOSOMA HAEMATOBIUM RECOMBINANT FUSION PROTEIN SHSAP AND APPLICATION THEREOF IN IMMUNODIAGNOSIS OF SCHISTOSOMIASIS

摘要

A Schistosoma haematobium recombinant fusion protein ShSAP and an application thereof in the immunodiagnosis of schistosomiasis. The Schistosoma haematobium recombinant fusion protein ShSAP can undergo large-scale standardized mass production by means of genetic engineering technology, antigen quality is stable and the repeatability of the results is good. The fusion protein can be used for the immunodiagnosis of both schistosomiasis haematosis and schistosomiasis mansoni, and has extremely high sensitivity. The Schistosoma haematobium recombinant fusion protein ShSAP has a single antigen component, and ShSAP-ELISA has excellent specificity for the immunodiagnosis of schistosomiasis. The fusion protein does not cross-react with the serum of a patient suffering from another parasitic disease, and has broad application prospects.