SINGLE DOMAIN ANTIBODY AND CHIMERIC ANTIGEN RECEPTOR COMPRISING ANTIBODY STRUCTURE

摘要

An antigen binding protein that targets BCMA, in particular a chimeric antigen receptor comprising the antigen binding protein, and an application thereof. The chimeric antigen receptor comprises an extracellular domain that targets BCMA, a transmembrane domain and an intracellular domain. The chimeric antigen receptor has a good killing effect on tumor cells in CAR-T therapy that uses BCMA as a target.