Suspension of sustained release containing dezosin analog ester and method for producing the same

摘要

The present invention discloses a sustained-release suspension containing a dezocin analog ester and a method for producing the same. In the present invention, an oil-based auxiliary agent and an excipient that can be pharmaceutically injectable as a sustained-release depot are selected, and a long-acting suspension for injection is used in combination with a pulverization technique, a high-pressure homogenization technique, and a poor solvent method. Succeeded in manufacturing. Its main components are compounds represented by the formula (I), oils for injection and the like. [Chemical 1]