Compounds for use in the treatment of neurogenic orthostatic hypotension

摘要

The present invention relates to 4- [2- (2,4,6-trifluorophenoxymethyl) phenyl] piperidine or a pharmaceutically acceptable salt thereof for the treatment of neurogenic orthostatic hypotension and symptoms thereof. Regarding use. In one aspect, there is provided a compound of formula I as described herein or a pharmaceutically acceptable salt thereof for use in the treatment of neurogenic orthostatic hypotension and symptoms thereof in a human patient. Is administered to the patient in an amount ranging from about 1 mg / day to about 20 mg / day, the use comprising (a) increasing the patient's sitting systolic blood pressure; (b) increasing the patient's standing time; Or (c) characterized by dizziness or reduced consciousness experienced by the patient.