The inventive concept relates to a system, a method and a program for estimating an acute cerebral infarction onset time. The method for estimating an acute cerebral infarction onset time according to one embodiment of the inventive concept comprises: a step of acquiring, by a computer, a first image (10) and a second image (20) of a specific first patient whose acute cerebral infarction onset time is not identified (S200; image receiving step); a step of extracting an infarction area image from the second image (20) (S400); a step of setting an infarction area in the first image (10) by matching the second image (20) to the first image (10) (S600); a step of extracting feature information of the first patient, from the infarction area in the first image (10) (S1000); a step of comparing the extracted feature information with reference data to calculate an amount of time that has elapsed since the acute cerebral infarction onset time, based on a result of the comparison of the extracted feature information with reference data (S1200).
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